Fixed low-dose triple combination antihypertensive medication vs. usual care for mild to moderate hypertension

New research out of Sri Lanka investigated whether a low-dose triple combination antihypertensive medication would achieve better blood pressure control compared with usual care. The randomized, open-label trial included adults with mild-to-moderate hypertension who required initiation or escalation of antihypertensive therapy.

New research out of Sri Lanka investigated whether a low-dose triple combination antihypertensive medication would achieve better blood pressure control compared with usual care. The randomized, open-label trial included adults with mild-to-moderate hypertension who required initiation or escalation of antihypertensive therapy. A total of 349 patients received a once-daily fixed-dose combination medication (20 mg of telmisartan, 2.5 mg of amlodipine, and 12.5 mg of chlorthalidone), while 351 received usual care. The primary outcome was the proportion of patients who reach the target blood pressure levels (